Producers and veterinarians trust First Defense to protect their dairy and beef calves

HYPERIMMUNIZED COLOSTRAL ANTIBODIES FOR SCOURS PREVENTION

Technology that protects calves and lowers your costs

ImmuCell is an animal health biologics company with hyperimmunization technology that enhances colostrum quality, amplifying nature’s most powerful defense. It delivers immediate immunity and increases the level of immunity against the common scours pathogens E. coli, coronavirus and rotavirus.

Read our hyperimmunization research summary

Work with a company that puts people over profit

You’d be right to believe we spend every day thinking about calf diarrhea. It may not sound glamorous, but having a grateful customer base with such high-energy enthusiasm for our products makes the poop business rewarding.

It takes fortitude, not armies of people and deep pockets, to champion products through both the USDA regulatory processes. We may be small, but we are determined to make a big difference in calf health for our customers.

Maximize the genetic potential of your calves

ImmuCell^® develops and manufactures scientifically proven scours prevention products to maximize the genetic potential of dairy and beef calves through disease prevention and reduced dependence on antibiotics.

We love what we do. In the lab, we pour our daily energies into the science of calf gut health and the manufacture of colostral antibodies. In the field, we’re helping producers solve calf health issues.

Talk directly to calf health experts

The distance between your problem and the solution at most animal health companies is three levels of management. It’s different here. We’re a closeknit, agile group known as the First Defense^® Calf Crew. We do one thing exceptionally well: prevent calf scours. When you call our Calf Crew, you’re talking directly with a scours prevention specialist.

“My sales rep is more like a sounding board. We talk calf health and because she and her team run in the same circles as the best calf raisers and researchers – her insights are especially valuable.”

Jackie McCarville

Calf Raiser & Dairy Extension Educator
Mineral Point, WI

Science is where we start

Doing things differently in animal health raises eyebrows. You want science and proof that our technology performs as promised. Science is where everything starts with us — like our research and science behind the structure and biology of rotavirus at Baylor College of Medicine that led us to develop Tri-Shield^® First Defense^®.

Science has made the First Defense product line a preferred way for dairy producers to prevent scours in newborn calves (Hoard’s Dairyman Continuing Market Study, 2025). We meet USDA and CFIA standards for efficacy, and our products are OMRI-listed.

Only ImmuCell hyperimmunizes bovine colostrum

ImmuCell is the only animal health company that hyperimmunizes bovine colostrum. We concentrate, purify and quantify specific colostrum antibodies (E. coli, coronavirus, and rotavirus) on a commercial scale for First Defense products – providing the best protection against scours, while reducing antibiotics in our food chain and maximizing the future productive capabilities of calves.

Learn about First Defense scours prevention

Our Purpose

Our team is led by people who have dedicated their careers to animal health. We have one purpose: Maximize the genetic potential of dairy and beef animals through disease prevention and reduced dependence on antibiotics.